Tetrahydrocannabinol has a long history of medical use as an analgesic. It was formally discovered by Dr. Raphael Mechoulam in 1964. Tetrahydrocannabinol has a molecular weight of 314.44g/mol and is naturally found in cannabis as a result of its secondary metabolism. THC behaves similarly to endo-cannabanoids found in the body near the neurons and can act interchangeably.
Exploiting cannabinoid and vanilloid mechanisms for epilepsy treatment.
Cannabinoids and the expanded endocannabinoid system in neurological disorders.
Pharmacology of cannabinoids in the treatment of epilepsy.
Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection.
Orally consumed cannabinoids provide long-lasting relief of allodynia in a mouse model of chronic neuropathic pain.
Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.
A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment.
Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis.
The Effectiveness of Cannabinoids in the Treatment of Posttraumatic Stress Disorder (PTSD): A Systematic Review.
Review of the neurological benefits of phytocannabinoids.