Linalool occurs in over 200 species of plants, commonly in lavender, rose and citrus. This terpene usually constitutes 5% or less of cannabis essential oil and has pleasant floral notes. Nevertheless, Linalool exhibits strong biological activity. Research studies showed that Linalool is one of the most powerful sedating terpene upon inhalation in mice.
Reduces opioids dependency
Effect of linalool on morphine tolerance and dependence in mice.
(-)-Linalool produces antinociception in two experimental models of pain.
Antidepressant activity of Litsea glaucescens essential oil: identification of β-pinene and linalool as active principles.
Inhaled linalool-induced sedation in mice.
Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils.
In vivo & in vitro
Anticonvulsant properties of linalool in glutamate-related seizure models.