D/L-Menthol – Terpene Profile
Menthol is mainly produced from mint oils and is commonly used in the food and pharma industry. It has a peppermint-like aroma and creates a cooling sensation when applied to skin and mucosal surfaces. There is a difference in the molecular structure between D- and L-menthol, which can be simplified by thinking of these molecules as the mirror image of one another. D-menthol has less cooling effects than its “mirrored sibling”. Several medical properties of menthol are discovered such as antimicrobial, anesthetic and antidepressive effects.
Local Anaesthetic Activity of (+)- and (-)-Menthol.
L-menthol exhibits antidepressive-like effects mediated by the modification of 5-HTergic, GABAergic and DAergic systems.
Preventing colonic spasms
Prevention of colonic spasm using l-menthol in colonoscopic examination.
Mechanisms of Antibacterial Action of Three Monoterpenes.