Sesquiterpenes
Alpha-Humulene – Terpene Profile
The name Humulene comes from the plant where it was first extracted from, Humulus Lupulus, also known as hops. Humulene can be up to 40% of the hops essential oil. In addition, its oxidation products in the brewing process give many beers their pleasant hoppy aroma. It has been shown to have antitumor activities.
Found in
Hops
Boiling Point
106℃
223℉
Medicinal qualities:
In vivo
Anti-inflammatory
Preventive and therapeutic anti-inflammatory properties of the sesquiterpene α-humulene in experimental airways allergic inflammation.
Rogerio, A. P., Andrade, E. L., Leite, D. F., Figueiredo, C. P., & Calixto, J. B. (2009)
Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea.
Fernandes, E. S., Passos, G. F., Medeiros, R., da Cunha, F. M., Ferreira, J., Campos, M. M., Pianowski, L. F., & Calixto, J. B. (2007)
In vitro
Anti-tumor
Antitumor activity of balsam fir oil: production of reactive oxygen species induced by alpha-humulene as possible mechanism of action.
Legault, J., Dahl, W., Debiton, E., Pichette, A., & Madelmont, J. C. (2003)
Cytotoxic activity of alpha-humulene and trans-caryophyllene from Salvia officinalis in animal and human tumor cells
El Hadri, A., del Río, M. A., Sanz, J., Coloma, A. G., Idaomar, M., Ozonas, B. R., González, J. B., & Reus, M. I. (2010)
Angiogenesis action
Wound Healing Effect of Essential Oil Extracted from Eugenia dysenterica DC (Myrtaceae) Leaves
Sandra Márcia Mazutti da Silva, Claudio Rodrigues Rezende Costa, Guilherme Martins Gelfuso, Eliete Neves Silva Guerra, Yanna Karla de Medeiros Nóbrega, Sueli Maria Gomes, Aline Pic-Taylor, Yris Maria Fonseca-Bazzo, Damaris Silveira, and Pérola de Oliveira Magalhães, (2019)
High α-Humulene strain-specific terpene formulations:
50ml / 1.7oz$26200
250ml / 8.4oz$1,09100