Wave of cyan particles

NT-VRL®

NT-VRL logo

Botanical terpenes for immune & inflammatory response support.

A patented 30-terpene formulation with peer-reviewed in-vitro evidence, built for brands seeking a documented functional ingredient.

NT-VRL® is a patented, data-driven terpene formulation developed and manufactured by Eybna. The formulation contains terpenes with a high indication for their anti-inflammatory & antiviral properties, in optimized ratios.

The formulation is based on Eybna’s proprietary phytochemical database, utilizing Eybna’s advanced data-mining and formulation design methodologies, to develop an effective and safe formulation. In order to evaluate NT-VRL® efficacy, the formulation was tested in two validated biological in-vitro models.

NT-VRL® exhibited inhibition of pro-inflammatory cytokines and antiviral activities, and even more profoundly when combined with CBD

2

Peer-reviewed publications

3

Viral models evaluated

4

Inflammatory markers measured

30

Terpenes in selected ratios

2024 · Biotechnology Reports

In a human-cell assay, NT-VRL® inhibited four inflammatory markers more strongly than the 1 µg/mL dexamethasone control.

In peer-reviewed testing on human immune cells, NT-VRL® produced dose-dependent inhibition of IL-1β, TNF-α, IL-6 and IL-8 without compromising cell viability.

In vitro only. Not a clinical comparison and not a therapeutic claim.

Peer Reviewed

Two studies. Three viruses. Four markers.

2021

Life

In Vitro Evaluation of the Activity of Terpenes and Cannabidiol against Human Coronavirus E229

  • Model

  • Principal constituents

  • Findings

  • DOI link

2024

Biotechnology Reports

Terpenes and Cannabidiol against Human Corona and Influenza Viruses

  • Model

  • Findings

  • Statistics

  • PubMed / DOI link

Microscope view of cell tissue

Thirty molecules, because one doesn’t work

Mechanism

Eybna's compound library — labelled drawers of terpene sample vials

NT-VRL® was built as a multi-compound formulation, selected from Eybna’s compound library and screened as combinations rather than isolated components.

The Platform Behind It

Designed on data, not on tradition.

A technician in cleanroom gear at a laboratory workstation

Eybna’s phytochemical database aggregates biological literature, in-vitro models, in-vivo literature and computational screening across botanical compounds.

Quality Standards

Certification stamp

Food Grade

Certification stamp

Only Natural Ingredients

Certification stamp

Solvent Free

Certification stamp

Botanical Derived

Certification stamp

OU Kosher

Certification stamp

Non GMO

Certifications

Safety Data Sheet

Safety Data Sheet

Certificate of Analysis

Certificate of Analysis

Technical Data Sheet

Technical Data Sheet

Natural Certificate

Natural Certificate

Certificate of Origin

Certificate of Origin

Food Grade Certificate

Food Grade Certificate

Allergen Checklist

Allergen Checklist

OU Kosher Certificate

OU Kosher Certificate

GMO Questionnaire

GMO Questionnaire

Work With Us

Three ways in, depending on what you’re building.

Formulate

Formulate with it

For supplement, beverage, topical and personal-care brands.

Licence

License the IP

For nutraceutical and pharmaceutical developers.

Build

Build something adjacent

For teams with a different biological outcome brief.

FAQs

What certificates do your products have?

Each of our products has an OU kosher certificate, cannabinoid, terpene, and microbiological certificate. Our CoA includes Cannabinoids, microbiology, and heavy metals. Other than CoA we provide SDS, CoO, GMO, and TDS.

Where can I find SDS and CoAs on your products?

We recommend reading the Safety Data Sheet before handling our terpene products. You can find the SDS and CoAs of each product at the bottom of the product page. If you have questions, contact the Support Team to further learn about the safe use of the terpene formulations.

Are Eybna terpenes food-grade?

We certify that all of our formulations are assembled only of materials allowed for use as flavor ingredients intended for human consumption, or as indirect additives according to Section 21 CFR of the Federal Food, Drug and Cosmetic Act. Also, we are compliant with the European Council Directive 88/388/EEC and EU Regulation 1334/2008.

Do you do customized terpene formulations?

Yes we do. We tailor make formulations to fit your exact needs and empower your brand. Based on your specifications, strain analysis are created from scratch according to your needs and product statement. Once developed, the custom formulation will be produced on a made-to-order basis and exclusively for you. Our dedicated development team guarantees a short turn-around time and non-compromised product satisfaction.

Do you sell large quantities?

Yes, we sell large wholesale quantities. For orders larger than 2 Liters, please Contact Us for volume pricing.

Where are your formulations produced?

Our formulations are developed and produced in our in-house laboratory in our R&D center based in Israel.